Adrenaline is added to lignocaine to prolong its effect and decrease its absorption into blood stream in a ratio of:

1:10,000- 1:2,00,000 adrenaline is used. . Name of the medicinal product Xylocaine 2% with Adrenaline (Epinephrine) 1:200,000. 2. Qualitative and quantitative composition Each ml of solution for injection contains lidocaine hydrochloride monohydrate Ph. Eur., equivalent to 20 mg of lidocaine hydrochloride anhydrous (400 mg per 20 ml l), 5 micrograms of adrenaline (epinephrine) as the acid tarate (100 micrograms per 20 ml l). Excipients with known effect: Each ml of solution also contains 0.5 mg sodium metabisulphite (E223), 1 mg methyl parahydroxybenzoate (E218) and 2.49 mg of sodium. For the full list of excipients, see section 6.1. 3. Pharmaceutical form Solution for injection 4. Clinical paiculars 4.1 Therapeutic indications Xylocaine 2% with Adrenaline is indicated for regional anaesthesia in adults and children above 12 years of age. From padmaja 4th edition Page no 96