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Pathology Systemic Pathology 93909775

All of the following are true statements about glioblastoma, except:

A
WHO grade IV tumour
B
Perineuronal satellitosis
C
Pseudo-palisading necrosis
D
Microvascular proliferation
High-Yield Explanation
Glioblastoma: Infiltrating astrocytoma and glioblastoma (the synonym for "grade IV astrocytoma") account for about 80% of primary brain tumors in adults. WHO grade IV astrocytic tumour On microscopy, necrosis (pseudo-pallisading) and/or microvascular proliferation are present Oligodendroglioma Fried egg appearance (perinuclear halo) Chicken wire capillaries (high degree of vascularization) Perineuronal satellitosis (Tumor cells that infiltrate the cerebral coex often collect around neurons) M/c mutation - IDH2 mutation

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