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Pathology Cardiovascular system 9350f276

ANCA positive vascuiltis is

A
Henoch schonlein purpura
B
Behcet'S syndrome
C
Wegener's granulomatosis
D
None
High-Yield Explanation
Wegener granulomatosis is a necrotizing vasculitis characterized by a specific triad of findings: * Granulomas of the lung and/or the upper respiratory tract (ear, nose, sinuses, throat) * Vasculitis of small to medium-sized vessels (capillaries, venules, aerioles, and aeries), most prominently in the lungs and upper respiratory tract * Glomerulonephritis PR3-ANCAs are present in almost 95% of cases and probably drive the subsequent tissue injury; Robbins Basic pathology,9th edition,pg no.353

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