Valproate is preferred over lithium in all of the following conditions except:
High-Yield Explanation
In elated or euphoric mania, lithium is preferred. In rest of the options, valproate is preferred. In renal compromise, lithium is avoided due to its renal side effects. Lithium Indications: 1. Acute manic episode 2. Bipolar depression 3. Maintenance treatment- it reduces severity, frequency and duration of both manic and depressive episodes 4. Antisuicide propey 5. Schizoaffective disorder 6. Major depressive disorder 7. Neutropenia 8. OCD 9. Headache (cluster headache, migraine) 10. Ulcerative colitis