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Gynaecology & Obstetrics General 930a2a2a

Acetic acid staining of cervix shows following exf-ent :

A
Squamous dysplasia
B
Cervical carcinoma in situ
C
Cervical polyp
D
Cervical dysplasia
High-Yield Explanation
Ans. is c i.e. Cervical polyp Colposcopy is the primary technique for evaluation of an abnormal cervical cytology smear.deg It is an outpatient procedure that is simple, quick and well tolerated. It allows excamination of the lower genital tract and anus with a microscope. Note : Upper 2/3 of endocervix is not visualized by colposcopy. While performing colposcopy, after visualization with naked eyes, acetic acid (3-5%) is applied for better visualization.deg Principle : - Application of acetic acid to normal epithelium : Glycogen producing epithelium of cervix does not produce any effect and its appears pink during colposcopy. Application of acetic acid to dysplastic epithelium : When acetic acid is applied to dysplastic epithelium-which have large nuclei with abnormally large amounts of chromatin (i.e. protein), acetic acid coagulates the proteins of the nucleus and cytoplasm, making the proteins opaque and white therefore Dysplastic cells and cancerous cells appear white Onovvr1 as Aceto white) (i.e. options "b" and -d" are correct). Application acetic acid to metaplastic epithelium : The immature metaplastic cells have large nuclei and also show some effects of the acetic acid. Since metaplastic epithelium is very thin, it does not appear white but instead appear Grey and filmy. (i.e. option "a" is correct).

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