True regarding Mitral valve prolapse syndrome is all,except-

MVP, also variously termed the systolic click-murmur syndrome, Barlow's syndrome, floppy-valve syndrome, and billowing mitral leaflet syndrome, MVP is more common in women and occurs most frequently between the ages of 15 and 30 years; Most patients are asymptomatic and remain so for their entire lives. Transient cerebral ischemic attacks secondary to emboli from the mitral valve due to endothelial disruption have been repoed. Infective endocarditis may occur in patients with MR and/or leaflet thickening. (Harrison's Principles of internal medicine, 18 th edition, page 1937 )