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Microbiology General 92ed18eb

Gastro-intestinal enteritis necroticans caused by:

A
CI difficile
B
CI. perfringens
C
Botulinum
D
C jejuni
High-Yield Explanation
“Necrotizing enteritis (enteritis necroticians, or pig bel) is caused by β toxin produced by type C strains of C.perfringens following ingestion of a high protein meal in conjunction with trypsin inhibitors by a susceptible host who has limited intestinal proteolytic activity”. Source of organism is patient own intestinal flora. Clinical features Acute abdominal pain, diarrhea, vomiting, shock and peritonitis, 40% of patient die. Pathological studies shows an acute ulcerative process of the bowel restricted to small intestine.

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