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Pharmacology C.N.S 92b3f0b9

An Anti epileptic drug, but NOT a mood stabalizer includes

A
Topiramate
B
Lamotrigine
C
Sodium valproate
D
Leviracetam
High-Yield Explanation
(D) Leviracetam# VALPROIC ACID: Available in extended release form. This drug can be very irritating to the stomach, especially when taken as valproic acid. Liver function and CBC should be monitored.> Lamotrigine: Particularly effective for bipolar depression. Usual dose is 100-200 mg daily, which can be built up by 25 mg every 2 weeks. The patient should be monitored for signs and symptoms of Stevens-Johnson syndrome, a very rare but potentially fatal skin condition.> Carbamazepine: CBC should be monitored, as carbamazepine can lower white blood cell count. Therapeutic drug monitoring is required. Carbamazepine was approved by the US Food and Drug Administration as a bipolar disorder treatment in 2005, but had been widely used previously.> Oxcarbazepine: Oxcarbazepine is not FDA approved for bipolar disorder. Still, it appears to be effective in about one-half of patients with bipolar disorder and be well tolerated.> Other anticonvulsants, such as gabapentin and topiramate, also are mood stabilizers.

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