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Pathology Irreversible cell Injury/Necrosis 92997790

CAR-T cells are used in the treatment of which of the following cancers?

A
Acute lymphoblastic leukemia
B
Soft tissue sarcoma
C
Medulloblastoma
D
Small cell lung carcinoma
High-Yield Explanation
CAR-T cells Chimeric antigen receptor (CAR) T cells are T-cells extracted from patient and modified in vitro to change T-cell receptor to detect specific protein on surface of malignant cells such as CD19 Currently approved for use in acute lymphoblastic leukemia and B-cell NHLs Examples of CAR-T cells are Kymria (ALL), Yescaa (DLBCL)

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