A 52-year-old woman is experiencing abdominal discomfort after meals as well as early in the morning. There is no weight loss or constitutional symptoms, and she has tried antacids but experiences minimal relief. Upper endoscopy reveals a duodenal ulcer and the biopsy is negative for malignancy. Which of the following is the most appropriate next step in management?
High-Yield Explanation
Antibiotic therapy for eradication of H pylori in combination with acid suppression with a proton pump inhibitor like omeprazole is the most effective treatment for duodenal ulcer disease. The most popular regimes include antibiotics and acid suppression medications.