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Medicine Virology 926c325d

Chances of vertical transmission of Hepatitis B are?

A
25-30%
B
40%
C
60%
D
90 to 95 %
High-Yield Explanation
ANSWER: (A) 25-30%REF: http ://www.who. int/maternal_child_adolescent/documents/pdfs/hepatitis_b_and_breastfe eding.pdfThe likelihood of perinatal transmission of HBV correlates with the presence of HBeAg and high-level viral replication; 65%-9Q% of HBeAg-positive mothers but only 10-15% of anti-HBe- positive mothers transmit HBV infection to their offspring. In most cases, acute infection in the neonate is clinically asymptomatic, but the child is very likely to remain chronically infected.However the article from WHO suggests that in Asia there is 20-40% chance of vertical transmission in HBeAg negative mothers also.

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