Binding of oxygen to haemoglobin reduces its affinity for carbon dioxide, which is known as

Increase in carbon dioxide in the blood causes oxygento be displaced from the hemoglobin (the Bohr effect). The reverse is also true: binding of oxygen with hemoglobin tends to displace carbon dioxidefrom the blood. Indeed, this effect, called the Haldane effect, Ref: Guyton & Hall: Textbook of Medical Physiology page no:946