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Gynaecology & Obstetrics Gynaecological oncology 9196611e

EMACO regimen of chemotherapy is used in the treatment of

A
Carcinoma cervix
B
Gestational trophoblastic neoplasia
C
Malignant Ovarian germ cell tumor
D
Endometrial carcinoma
High-Yield Explanation
EMA-CO a cyclic non, cross-resistant combination of etoposide, methotrexate, and actinomycin D alternating with cyclophosphamide and vincristine.Etoposide induces complete remission in 95% of patients with nonmetastatic and low-risk metastatic GTN. The use of EMA-CO induced an 83% remission rate in patients with metastasis and a high-risk score.Ref: Berek and Novak&;s Gynecology; 15th edition; Chapter 39 Gestational Trophoblastic Disease

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