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Pharmacology General 916787ae

Which of the following statements regarding tigecycline is true?

A
It is a bactericidal drug
B
It does not require dose adjustment in renal failure
C
Approximately 95% of pseudomonas are susceptible to tigecycline
D
It has narrow spectrum antibacterial action
High-Yield Explanation
Tigecycline is a wide spectrum protein synthesis inhibitor but is less effective in treating pseudomonal infection.  It belongs to tetracycline group of drugs and all tetracyclines are bacteriostatic and require dose reduction in renal insufficiency.

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