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Surgery General 913a680b

All of the following are histopathological findings of papillary carcinoma, except

A
Orphan Annie eye nuclei
B
Psammoma bodies
C
Monofocal papillary projections
D
Intranuclear grooves
High-Yield Explanation
Pathology Papillary projections Psammoma bodies (concentric calcifications) Pale empty (orphan annie) nuclei → FINELY DISPERSED CHROMATIN IMPARTS AN EMPTY APPEARANCE Intranuclear grooves and nuclear characteristics are diagnostic of papillary carcinoma Multifocality is common in papillary carcinoma TSH levels are high; tumors are TSH dependent, hence follow-up with TSH. Key Concept: Multifocality is common (up to 85% of cases) on microscopic examination. Multifocality is associated with an increased risk of cervical nodal metastases, rarely invade adjacent structures such as the trachea, esophagus, and RLNs. RLN implies lymph nodes.

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