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Pathology Inflammation & Repair 910321ff

C3a, C5a are called?

A
Chemotactic agent
B
Lytic complex
C
Opsonins
D
Anphylotoxins
High-Yield Explanation
Ans. is 'd' i.e., Anaphylotoxins * C5a, C3a 8c to a lesser extent C4a- are called anaphylotoxin because they have effects similar to those of mast cell mediators that are involved in the reaction called anaphylaxis. These effects are due to stimulation of histamine release by these anaphylotoxin. The effects are increased vascular permeability and vasodilatation.

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