All of the following agents decreases bone resorption in osteoporosis, Except -
High-Yield Explanation
A drug used in osteoporosis
Inhibit resorption: - Bisphosphonates, denosumab, cinacalcet, calcitonin, estrogen, SERMS, gallium nitrate.
Stimulateformation : -Teriparatide, calcium, calcitrial, fluorides,.
Both actions : - Strontium, renelate.
Drugs decreasing bone resorption initially increase bone mineral density (BMI), but it reaches a plateau in 2-3 yrs because bone formation also decreases.
On the other hand, drugs promoting bone formation can increase BMD through the period of treatment.