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Pharmacology General 90076952

Which laxative acts by opening of Chloride channels ?

A
Docusate
B
Anthraquinone
C
Lubiprostone
D
Bisacodyl
High-Yield Explanation
Ans. is 'c' i.e., Lubiprostone o Lubiprostone is used for chronic constipation, it acts by - o Stimulating Cl- channel opening in the intestine. Increasing liquid secretion in gut. Decreasing transit time.

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