A patient has serum creatinine of 150-300 micromol/L. Which of the following require dosage reduction: March 2011
High-Yield Explanation
Ans. C: Gentamycin Drugs whose dosage are affected in mild renal insufficiency (GFR 20-50 mL/ min or serum creatinine 150-300 micromol/L) are: ACE inhibitors, Aminoglycosides, chlorpropamide, digoxin, fibrates, lithium and zidovudine