Drug with beta adrenergic blocking, with antioxidant, with calcium channel blocking, with alpha 1 antagonist activity is ?
High-Yield Explanation
Ans. is 'b' i.e., Carvedilol Carvedilol Carvedilol is a b1 + b2 + a1 adrenoceptor blocker with a : b blocking propey of 1 : 9. It has antioxidant and antimitotic propey. It produces peripheral vasodilation due to a-1 blockade as well as calcium channel blockade (direct effect). It is used in hypeension and angina. It is used as cardioprotective in CHF. t1/2 is 2-8 hrs. It is eliminated through liver and kidney. It causes ohostatic hypotension.