Pharmacology General 8f0cd6b7

Rofecoxib as compared to indomethacin is :

Less likely to cause gastric ulcer and their complications

Likely to be more effective in rheumatoid arthritis

Not likely to produce renal complications

All of the above

High-Yield Explanation

Selective COX-2 inhibitors are less likely to cause GI complications like PUD. However a COX-2 is also present constitutively in the kidney, chances of renal complications are similar. These drugs have similar or less efficacy than non-selective COX inhibitors.

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