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Microbiology General 8f04c40b

The term MHC restriction refers to which of the following statements?

A
Inheritance of MHC molecules
B
Need for antigen to be recognized in association with MHC molecules
C
Need for MHC genes to control complement activity
D
Need for MHC molecules in order to reject grafts
High-Yield Explanation
MHC class I- or class II-restriction means that T cells recognize antigen peptide fragments only when they are presented in the antigen-recognition site of a class I (for CD8+ T cells) or class II MHC molecule(for CD4+ T cells), respectively.

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