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Pharmacology Immunomodulators 8eef54ce

A pregnant woman of >35 weeks gestation has SLE. All of the following drugs are used in treatment except:

A
Methotrexate
B
Sulfasalazine
C
Prednisolone
D
Chloroquine
High-Yield Explanation
Methotrexate is very effective in treating Systemic Lupus erythematosus(SLE) but during pregnancy, it can cross the placenta and cause the teratogenic effect to the fetus. The main teratogenic effect caused by Methotrexate is cleft palate, hydrocephalus, multiple defect, and fetal death. ESSENTIALS OF MEDICAL PHARMACOLOGY: SEVENTH EDITION -K.D TRIPATHI Page:862,89

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