Iron is predominantly absorbed in

Almost all iron absorption occurs in the duodenum. Transpo of Fe2+ into the enterocytes occurs divalent metal transpoer 1 (DMT1). Some are stored in ferritin, and the remainder is transpoed out of the enterocytes by a basolateral transpoer named ferropoin 1. A protein called hephaestin (Hp) is associated with ferropoin 1. It is not a transpoer itself, but it facilitates basolateral transpo. In the plasma, Fe2+ is conveed to Fe3+ and bound to the iron transpo protein transferrin. This protein has two iron-binding sites. Normally, transferrin is about 35% saturated with iron, and the normal plasma iron level is about 130 mg/dL (23 mmol/L) in men and 110 mg/dL (19 mmol/L) in women.Ref: Ganong&;s review of medical physiology 23rd edition Page no: 452