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Microbiology General 8e8d7d01

Killer cells are associated with type ..... immunologic response -

A
Type I
B
Type II
C
Type III
D
None
High-Yield Explanation
Ans. is D - 'None' . Killer cells are antibody dependent cytotoxic cells (ADCC) a type of Null cells. . "The role of ADCC in hypersensitivity diseases is unceain". Don't get confused between type II hypersensitivity and antibody dependent cellular cytotoxicity (ADCC). . Type II hypersensitivity is mediated by antibodies directed toward antigens present on cell surfaces or extracellular matrix. It involves opsonization i.e., complement and Fc receptor mediated phagocytosis. . Antibody-mediated destruction of cells may occur by another process called antibody dependent cellular cytotoxicity (ADCC). It is different from Type II hypersensitivity. It does not involve fixation of complement but instead requires the co-operation of leukocytes i.e., antibody dependent cytotoxic cells (ADCC). It is not a type II hypersensitivity.

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