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Physiology Excitation and Action Potiential 8e82726e

At the end of repolarization, the nerve is hyperpolarized. How does the membrane potential return to RMP?

A
Action of Na+/ K+ -pump
B
Inward leakage of Na+
C
Decrease in K+ efflux
D
None of the above mechanisms
High-Yield Explanation
Simultaneously with the action of the pump, there is inward diffusion of Na+ through the leaky channels (not the voltage-gated channels that cause depolarization). This inward leakage of positive charges will take the membrane potential from - 90 mV to original RMP of - 70 mV. Both the pump and the inward leakage will balance out once the potential again reaches - 70 mV.

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