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Pharmacology Adrenal 8dbf324c

Long term steroid therapy can lead to suppression of hypothalamic-pituitary- adrenal axis. It can be overcome by using alternate day therapy with coicosteroids. Which of the following steroids are unsuitable for alternate day therapy for such purpose?

A
Coisol
B
Prednisolone
C
Betamethasone
D
Hydrocoisone
High-Yield Explanation
Glucocoicoids : Anti-inflammatory Sho acting : Coisone, Hydrocoisone Intermediate : Prednisone, Prednisolone, Triamcinolone Long acting : Dexamethasone, Betamethasone and Paramethasone Betamethasone is long acting having half life 36-72 hrs so it is not suitable for alternate day therapy as it will not be excreted out till the time of next dose.

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