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Pathology Misc. 8da0f643

"Macropolycyte" in peripheral smear is a feature of

A
Hereditary spherocytosis
B
Iron deficiency anaemia
C
Sickle cell anaemia
D
Megaloblastic anaemia
High-Yield Explanation
(D) Megaloblastic anaemia # Certain morphologic features are common to all forms of MEGALOBLASTIC ANEMIA.> The peripheral blood reveals marked variation in the size & shape of red cells (Anisocytosis), which are nonetheless normochromic.> Many erythrocytes are macrocytic & oval (macroovalocytes), with mean corpuscular volumes above 100 mm3 (normal, 82 to 92).> Neutrophils too are larger than normal (macro polymorphonuclear) & are hypersegmented, that is, have five to six or more nuclear lobules.

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