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Pharmacology General 8d8142db

Pulmonary fibrosis is a side effect of: March 2012

A
Mitomycin-C
B
Hydroxyurea
C
Bleomycin
D
Cisplatin
High-Yield Explanation
Ans: C i.e. Bleomyci Drugs and side-effects Mitomycin-C's primary targets of toxicity are bone marrow and gastrointestinal tract. Major toxicity of hydroxyurea is myelosuppression. Mucocutaneous toxicity and pulmonary fibrosis, but little myelosuppression are the special features of bleomycin toxicity. The most impoant toxicity of cisplatin is renal impairment. Cisplatin is highly emetic drug.

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