Pathology Haematology 8d5a35c3

Classical markers for Hodgkin&;s disease-

CD 15 and CD 30

CD 15 and CD 22

CD 15 and CD 20

CD 20 and CD 30

High-Yield Explanation

Immunophenotyping of RS cells reveals monoclonal lymphoid cell origin of RS cell from B cells of the germinal centre in most subtypes of Hodgkin&;s disease. RS cells in all types of HD, except lymphocyte predominance type express immunoreactivity for CD15 and CD30.Therefore they ard considered as the classical markers for HD. REFERENCE; Harsh Mohan textbook of pathology,7th edition.Pg no.349

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