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Pharmacology Autonomic nervous system 8d4ba708

Dopamine is preferred in treatment of shock because of

A
Renal vasodilatory effect
B
increased cardiac output
C
Peripheral vasoconstruction
D
Prolonged action
High-Yield Explanation
ref; KD Tripathi 6th edition pharmacology (page no;134) Dopamine (DA) is a dopaminergic (D1 and D2) as well as adrenergic alps 1 &b 1 (but not b2 ) agonist. The D1 receptors in renal and mesenteric blood vessels are the most sensitive: i.v. infusion of a low dose of DA dilates these vessels (by raising intracellular cAMP). This increases GFR and Na+ excretion.

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