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Unknown General 8d3420cf

Increased blood levels of cholesterol that are seen in hypothyroidism are most likely due to -

A
Decreased calorigenesis
B
Decreased production of LDL receptor in liver and the thus decreased clearance by liver
C
Decreased production of LDL receptor in the adipose tissue and increased release of cholesterol from adipose tissues
D
Increased breakdown of lipoproteins releasing cholesterol in circulation
High-Yield Explanation
Ans- B Thyroid hormone increases the hepatic expression of LDL receptor. Hence in hypothyroidism there is reduction in hepatic LDL receptor So there is reduced clearance of LDL.

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