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Microbiology Immunology 8ce3ffb3

A pregnant 21-year-old Rh-negative female is about to deliver. The baby's father is determined to be Rh-positive. To reduce the chance for the development of hemolytic disease of the newborn, which of the following procedures should you order?

A
Administration of anti-Rh antibodies to the fetus postdelivery
B
Administration of anti-Rh antibodies to the mother postdelivery
C
Immediate blood transfusion of the suspected father
D
Immediate blood transfusion of the mother with Rh-positive blood
High-Yield Explanation
Anti-Rh antibodies (IgG are reactive at 98.6degF ) are the leading cause of hemolytic disease of the newborn (HDN). Currently, Rh immunization can be suppressed in antepartum or postpartum Rh-women if high-titer anti-Rh immunoglobulin (Rh Ig) is administered within 72 hours after the potentially sensitizing dose of Rh+ cells (i.e., the birth of the child). The other choices will do nothing to prevent the development of HDN in future pregnancies.

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