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Biochemistry Molecular Genetics 8cc45c14

Retinoblastoma can result from a mutation in:

A
Ras proto-oncogene
B
ErbB proto-oncogene
C
p 53 gene
D
RB 1 gene
High-Yield Explanation
Ans. D. RB 1 geneRetinoblastoma is a cancer common in children below 15 years of age. Itis caused by abnormalities of a gene called RB1, which is located on a region of the long (q) arm of chromosome 13 designated 13q14. Although most retinoblastomas are caused by mutations within the RB1 gene, a small percentage of retinoblastomas result from a deletion of the 13q14 region.

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