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Biochemistry Cholesterol synthesis and bile acids 8c8c7a98

Which of the following is not synthesised from mevalonate?

A
Farnesyl pyrophosphate
B
Geranyl pyrophosphate
C
Dolichol
D
Ubiquitin
High-Yield Explanation
Cholesterol synthetic pathway is also involved in the synthesis of many other impoant compounds such as: Farnesyl pyrophosphate and geranyl pyrophosphate - involved in prenylation of proteins. Dolichol - involved in N-glycosylation of proteins in endoplasmic reticulum. Ubiquinone (Q10) - is the electron carrier in the mitochondrial respiratory chain. Inhibition of ubiquinone synthesis is one of the reasons for statin-induced myopathy. Ubiquitin protein is not synthesized by any of the cholesterol synthesis pathway intermediate.

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