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Pharmacology C.V.S 8c74ca8c

Digoxin is contraindicated in:

A
Supraventricular tachycardia
B
Atrial fibrillation
C
Congestive heart failure
D
Hypertrophic obstructive cardiomyopathy
High-Yield Explanation
Ans. (D) Hypertrophic obstructive cardiomyopathy(Ref: KDT 8th/e p560, 561)Non selective b-blockers (propranolol) are the agents of choice for HOCM.In hypertrophic obstructive cardiomyopathy (HOCM), the LV outflow tract is narrowed during systole due to hypertrophic septum. Obstruction is worsened by:(a) Factors increasing myocardial contractility.-Digitalis-Sympathetic stimulation(b) Factors decreasing LV filling:-Valsalva maneuver-Peripheral vasodilators

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