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Pediatrics Genetics And Genetic Disorders 8c3f3cbb

% of offsprings affected by colour blindness, of a healthy male and heterozygous female:

A
None
B
25%
C
50%
D
100%
High-Yield Explanation
b. 25%(Ref: Nelson's 20/e p 642; Ghai 8/e p 641)Color blindness is an X-linked recessive disorder.In X-linked disorders, if father is normal and mother is a carrier, 50% of children will inherit defective X chromosome.Out of these, the daughters (having 1 normal and 1 defective X chromosome) will act as carriersWhile, all sons, inheriting the defective X chromosome will be affected by colour blindness. Hence, 25% of children will be affected.

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