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Physiology General 8c0a71ef

Voltage gated sodium channels are?

A
Multimeric
B
Pentameric
C
Heterotrimer
D
Monomeric
High-Yield Explanation
Ans. is 'c' i.e., Heterotrimer lRef: Principles of medical physiology p. 24There are two different types of Sodium channels:-l) Voltage-gated sodium channel:These Are Present inExcitable cells.These exist as heterodimers or heterotrimers of alpha and beta subunits, containing one alpha and one or two betasubunits.2) Epithelial sodium channels:These are present in the epithelium of absorptive or secretory epithelium,e.g. colon, sweat gland duct, pancreatic duct, respiratory passage, and distal tubule of kidney.These exist as heterotetramers of alpha, beta and gamma subunits, containing mostly two alpha, one beta and one gamma subunits.

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