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Physiology Heart, Circulation, and Blood 8bdfbcfd

Rapid depolarization (phase 0) of the action potential of ventricular muscle results from opening of:

A
Voltage-gated Ca2+ channels
B
Voltage-gated Na+ channels
C
Acetylcholine-activated K+ channels
D
Inward rectifying K+ channels
High-Yield Explanation
Ans. B. Voltage-gated Na+ channelsVoltage-gated Na+ channels are responsible for phase 0 in ventricular muscle. Voltage gated Ca2+ channels are responsible for phase 0 in nodal cells. The potassium channels mentioned do not play a role in mediating depolarization.

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