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Pharmacology Chemotherapy 8b8d42f8

True statement regarding development of drug resistance in MRSA is

A
Results due to pencillinase enzyme production
B
Occurs due to change in penicillin -binding proteins
C
Chromosome mediated
D
Treated with amoxicillin +clavulanix acid
High-Yield Explanation
Ref Katzung 11/e p776 Methicillin resistance occurs due to altered PBPs6, thus no penicillin (infant no beta lactam antibiotic) is useful against Methicillin -resistant Staphylococcus Audrie infections

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