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Pathology Cardiovascular system 8b5d6683

Factor responsible for Cardiac Hyperophly is?

A
ANF
B
TNF alpha
C
c-myc
D
TGF beta
High-Yield Explanation
Myc (c-Myc) is a regulator gene that codes for a transcription factor. The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. A mutated version of Myc is found in many cancers, which causes Myc to be constitutively (persistently) expressed. This leads to the unregulated expression of many genes, some of which are involved in cell proliferation Robbins 9 th edition page no. 367

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