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Pathology miscellaneous 8ac3253a

Based on the appearance of these two siblings, which pharyngeal arch appears to be most affected?

A
Pharyngeal arch 1
B
Pharyngeal arch 2
C
Pharyngeal arch 3
D
Pharyngeal arch 4
High-Yield Explanation
Here both siblings show mandibular hypoplasia. Mandible develops from 1st pharyngeal arch Pierre Robin sequence and Treacher Collins syndrome are both associated with mandibular hypoplasia.

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