Monitoring of β-HCG Useful in Management ofa) H.moleb) Choriocarcinomac) Ectopic Pregnancyd) Endodermal Sinus Tumor

β-hCG levels are helpful in monitoring: a. H. mole: “ A method of detecting the persistent mole and development of choriocarcinoma is by estimating hCG is the serumurine”. Shaw 14/e, p 231 b. Chorio carcinoma: β-hCG is a specific marker for choriocarcinoma. The levels of b-hCG are monitored following chemotherapy and complete regression of tumor is indicated when three consecutive weekly radioimmunoassays of hCG in serum are negative. Shaw 14/e, p 235 c. Ectopic pregrancy: In case of unruptured ectopic pregnancy which is managed medically with methotrexate or by conservative surgerymonitoring is done by estimating β-hCG levels. “Following conservative surgery or medical treatment ,estimation of β-hCG should be done weekly till the value becomes < 5.0 mIU/ml” Dutta Obs 6/e, p 191 d. Endodermal sinus tumor- ‘These tumors are yolk sac tumors and their markers are Alpha fetoprotein and antityrypsinso their levels and not betahCG. So hCG levels are not used for monitoring. Shaw 14/e, p 380