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Pharmacology General 8a6f7a30

Resistance to zidovirdine develops due to:

A

Mutation at reverse transcriptase

B

Increased efflux of the drug from inside the cell

C

Increased metabolism of the drug

D

Decreased zidovudine triphosphate formation

High-Yield Explanation

"Resistance to AZT (Zidovudine) occurs by point mutations which alter the reverse transcriptase enzyme,"

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