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Gynaecology & Obstetrics General 8a59373d

A female presents with leaking and meconum stained liquior at 32 weaks. She is infected with

A
CMV
B
Listeria
C
Toxoplasma
D
Herpes
High-Yield Explanation
“Discolored brownish or meconium stained amniotic fluid is common with fetal infection, even with preterm gestation” Hence, the correct answer is Listeria, rest of the infections do not lead to preterm labour with meconium stained liquor. Listeriosis Causative organism- listeria monocytogenes (facultative intracellular gram positive bacillus) Mode of infection- Food-borne infection caused by eating food like raw vegetables, Coleslaw, Apple cider, Melons, Milk, Fresh mexican style cheese, Smoked fish, Processed foods. Clinical features Can be asymptomatic Can cause febrile illness. Maternal complications which can occur due to listeria infection are: Preterm labor, Chorioamnionitis, Menonium stained liquor, Abortions, Placental Macroabscesses Maternal infection can lead to fetal infection characterised by: Disseminated granulomatous lesions with microabscess in skin Stillbirth Overall perinatal mortality-50%. Management Drug of choice is combination of Ampicillin + gentamicin or in case of pencillin allergy – Trimethoprim sulfamethoxazole Maternal treatment may be effective for fetal infection There is no vaccine for listeriosis.

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