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Anaesthesia General 89e3ebc8

An ICU patient on atracurium infusion develops seizures after 2 days. The most probable cause is –

A
Accumulation of landonosine
B
Allergy to drug
C
Due to prolong infusion
D
All of the above
High-Yield Explanation
Hofmann degradation of atracurium produces tertiary metabolite laudanosine which can cross blood brain barrier and produces convulsions.
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