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Pediatrics General 89c46e0f

A child has tnicrocephaly, blue eyes, Fair skin, and Mental retardation, Ferric chloride test is positive.What is the likely diagnosis -

A
Phenylketonuria (PKU)
B
Homocystinuria
C
Tyrosinosis
D
Alkaptonuria
High-Yield Explanation
Clinical manifestations of phenylketonuria Normal at birth Symptoms occur after 1 months - Mental retardation → Not present at birth, develops gradually. Neurological signs Irritability, tremors, convulsions, hyperkinesis and muscular hypertonia & exaggerated reflex. Blond hair, blue iris, fair skin. Musty or mousy body odor. Vomiting Microcephaly Enamel hypoplasia & Growth retardation

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