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Pharmacology General 89c14dd8

What is the treatment for headache in a case of peptic ulcer disease?

A
Microline aspirin
B
Propoxyphene
C
Paracetamol
D
Oxyphenbutazone
High-Yield Explanation
Propoxyphene binds primarily to opioid receptors and produces analgesia and other CNS effects that are similar to those seen with morphine-like opioids. It is likely that at equianalgesic doses the incidence of side effects such as nausea, anorexia, constipation, abdominal pain, and drowsiness are similar to those of codeine. All other choices produce gastric ulceration. Ref: Yaksh T.L., Wallace M.S. (2011). Chapter 18. Opioids, Analgesia, and Pain Management. In L.L. Brunton, B.A. Chabner, B.C. Knollmann (Eds), Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e.

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