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Biochemistry Respiratory chain 89945912

Malonate is a competitive inhibitor of

A
Complex I
B
Complex II
C
Complex III
D
Complex IV
High-Yield Explanation
Barbiturates such as amobarbital inhibit electron transpo Complex I by blocking the transfer from Fe-S to Q. At sufficient dosage, they are fatal in vivo. Antimycin A and dimercaprol inhibit the respiratory chain at Complex III. The classic poisons H2S, carbon monoxide, and cyanide inhibit Complex IV and can therefore totally arrest respiration. Malonate is a competitive inhibitor of Complex II Reference: Harper; 30th edition; Page no: 132

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