Which of the following is associated with hypersensitivity pneumonitis -
High-Yield Explanation
Hypersensitivity pneumonitis
Hypersensitivity pneumonitis describes a spectrum of immunologically mediated*, predominantly interstitial lung disorders caused by intense, often prolonged exposure to inhaled organic dust and related occupational antigens.
Etiology: Inhalation of organic dust, most commonly spores of thermophilic fungi*.
Depending on the occupation or exposure of specific antigen numerous names have been given to hypersensitivity pneumonitis.
Farmer's lung → Thermophilic actinomycetes on mouldy hay or grain dust.
Pigeon breeder's lung → Proteins from serum, excreta or feathers of the birds.
Air conditioner lung (or Humidifier lung) → Thermophilic bacteria in heated water reservoirs.
Bagassosis → Sugarcane bagasse
Byssinosis → Cotton dust
Maple-bark disease → Mouldy maple bark
Mushroom-worker's lung → Mushroom compost dust
Silo-filler's disease → Toxic fumes of NO & N2O due to fermentation of silage